Rerum® 3ml vial (3rd generation GcMAF)


New product

1 x 3ml vial of Rerum® "Advanced Immune Support"

A micro-sized emulsion of...

  • Oleic Acid
  • Chondroitin
  • Cholecalciferol
  • Ergocalciferol

"the secret is in the molecular bonding"

Store: cool, dry, closed, and protected from light.

Created by Molecular Biologist, Professor Marco Ruggiero, MD, PhD.

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rating Read the 22 reviews
Average rating: 9/10 - Number of reviews: 22


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Rerum® emulsion implements a new carrier system. The compound of Chondroitin, Oleic Acid, Vitamin D3 and Vitamin D2 provides the support for Macrophage Activation, that previously was assumed to GcMAF.

Ingredients: Ultrapure water, chondroitin sulfate, oleic acid, cholecalciferol, ergocalciferol

Store: cool, dry, closed, and protected from light (a dark cupboard).
Transport: protected from light, at room temperature. Rerum is heat stable.
Best before: one year from date of manufacture (lasts twice as long if refrigerated).
Once opened: store refrigerated (< 8 °C) and closed. If oral adapter used (membrane wide open) then use contents within 30 days. If a sterile needled syringe is used (membrane intact, contents sterile) then use contents within 12 weeks.

Rerum® Dosage Recommendations

Note: Chondroitin Sulfate has a blood thinning effect similar to heparin, so when taking larger doses, people on anticoagulant drugs, are advised to be under medical supervision.

Shake well to homogenize the emulsion (product separation is typical and no quality defect).

  • Start with 0.2ml (4 drops) every weekday (5 days a week). Continue on this cycle.
  • For greater immune support, take 0.5ml (10 drops) every weekday. Continue on this cycle.
  • For maximum immune support, take up to 1ml every weekday. Reduce dose to 0.5ml after desired effects are noticed (generally 2 to 4 weeks).

NOTE: Sensitive adults should start with 0.1ml (2 drops) every 3 days. Gradually increase or reduce dose as tolerated to create desired effect.

Recommended Dose for Sensitive Children (titrate up from 0.02 ml)
15 to 20 kg   (33 to 44 lbs)0.04 ml4weekly
20 to 25 kg   (44 to 55 lbs)0.05 ml5weekly
25 to 30 kg   (55 to 66 lbs)0.06 ml6weekly
30 to 35 kg   (66 to 77 lbs)0.07 ml7weekly
35 to 40 kg   (77 to 88 lbs)0.08 ml8weekly
40 to 45 kg   (88 to 99 lbs)0.09 ml9weekly
45+ kg   (99+ lbs)0.1 to 0.25 ml10 to 25weekly



Orally - under the tongue

  • Product is sterile and may be administered sublingually (under the tongue).
  • Keep in the mouth for at least 2 minutes to support absorption by the oral mucosa.
  • Then swallow. The bioavailability of Rerum® is increased by digestion.
  • Do NOT drink or eat for at least 30 minutes after taking.


Rerum® may be used for beautiful skin

  • Shake well to homogenize the emulsion (product separation is typical and no quality defect)
  • Withdraw 0.2ml from vial for topical application to skin via sponge.
  • Massage Rerum® sparingly onto face and neck with a gentle patting motion.

How to Load Supplied Needleless Syringe

Note: 1 x blue ring apparatus, needleless syringe, "H" connector & combi-stopper (as shown below) supplied as standard.

Installing Oral Adaptor to Rerum Vial
  1. Prise blue or white tampertel disk from top of vial.
  2. Install "blue ring apparatus" to top of vial as seen in above 4 image sequence. Be careful to keep vial upright so as not to spill contents.
  3. Twist the short end of the white "H" connector into the top of the blue ring apparatus. (approx 1/4 turn until firm)
  4. Then locate closed syringe into top of "H" connector so now connected to vial in airtight seal.
  5. Invert vial, with syringe underneath, and draw syringe open to the required amount (i.e. 0.2ml).
  6. Turn vial upright and remove syringe from vial. Place upright vial carefully away and administer dose.

Note: Vial to be resealed by untwisting "H" connector from top of the blue ring apparatus and twisting the blue combi-stopper onto the apparatus.

Installing Syringe to Rerum Vial

Note: every division on the supplied 3ml oral syringe equals 0.1ml. Accurate smaller doses (0.01ml) require a different syringe. In these cases we recommend using an insulin syringe and removing the Rerum from the vial directly i.e. without the oral adapter.

QuantityDiscountYou Save
3 NZ$285.48 Up to NZ$856.44
10 NZ$302.22 Up to NZ$3,022.20


Instructions for Rerum dosage and administration

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Using Rerum to support Beautiful Skin

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Click here to leave a review

See Improvement
Rita P. on 27/06/2017I have seen improvement with this product. I feel more together, more stamina. Will continue to take.
Irene L. on 19/06/2017

Discontinued RERUM BLUE and now on RERUM for my 7yr old son who's is ASD . Results are slow and occur over a prolonged period of time . Would love to know more on how long he should be on this protocol as it's very expensive to continue indefinitely . More information on ASD children and it's use would be appreciated on the website .


Rerum is sold as a nutritional supplement, and as such we are restricted by law from commenting on any therapeutic use that doctors may recommend it for.

Gives Me Hope
David E. on 14/06/2017Hopefully it will work the way it's supposed to
still working on it
Victoria l. on 28/05/2017we tried rerum for last 5 weeks, my son did not have some obviously change in terms of him languages and behaviors grogress. However on some of degrees, his attention had improved a little. i wish he could get some major benefits from this product later on.
3 weeks in
Rita P. on 16/05/2017started with 4 drops x5days increased to 10 drops and am feeling positive effects.
Larry B. on 23/04/2017Noticed improvement with double vision arm strength and Energy levels have not finish the first vial yet
Bill H. on 11/04/2017

Have been utilizing retum for a half year so far. Fighting cancer has many unknowns among them the mystery of knowing how the protocols are performing.. cost factors are burdensome but we keep forging foward.

Gail Portanova, M.D. - Stage 4 Endometrial Cancer
Gail P. on 29/03/2017

Rerum has brought me excellent results in 6 months. Tumors are shrinking markedly.

Mary Ellen H. on 08/03/2017Excellent product. And excellent help over the phone
Bravo and Rerum
Steven L. on 02/03/2017Hello, I regretfully state that after 3 months the products seem to have no effect. I ingest amino acid tablets,eat and supplement with turmeric,juice and am mostly in ketosis. I find after taking Bravo I immediately hack up phlegm which indicates that I'm not able to tolerate the product.
Answer: This demonstrates the importance of being in a high state of ketosis. Mostly in ketosis is not good enough. It is the ketosis that starves the cancer cells and makes them visible to the immune system. Aim for average levels of 2.5 as measured by a finger prick meter. Also Bravo suppositories should be used instead of Bravo drink if Bravo drink not tolerated. Finally, forget tumeric. The active ingredient we want is Curcumin which is 3% (or less) of tumeric. Use UltraCur, which is water soluble curcumin.
Stephanie M. on 28/02/2017After 3 months of Rerum, my lung metastases have gone but the primary breast tumor has stayed the same. At least it has not gotten bigger and I hope continued use will see better results.
Answer: Rerum supports the immune system to fight cancer. You need the ketogenic diet and high states of dietary ketosis as measured by a finger prick meter to starve the cancer and help make it visible to the immune system. Increasing your ketogenic state will provide better results.
Looks promising
Maria M. on 23/01/2017Just started using this product. Hope for excellent results.
RERUM 3 ml vial
Antionette P. on 28/12/2016My son has severe autism. I have not seen any improvement for a recovery I will keep using the RERUM. May be it takes time, Sorry
Answer: Yes results from the support Rerum offers can easily take longer than two weeks to manifest and best results are achieved when used with Bravo Probiotic and the ketogenic diet.
Wayne R.
Wayne R. on 29/11/2016I've been using Bravo Yoghurt and Rerum for nearly 4 months and included the Keto diet 2 months ago. My last scan showed a great turnaround in my cancer with the sarcoma in my thigh halving in size. Many thanks to Michael for his help and great service.
valerie g
Valerie G K. on 05/12/2016only time will tell as i use it
Steven L. on 26/11/2016The support staff was incredibly helpful in all areas. I 've been on the product for 2 weeks now and am being patient for positive results.
This product really helped me
Joan W. on 22/10/2016This product really helped pull me through a tough health crisis, looking forward to getting my next order. Thank-you! Joanee
kimberly C. on 12/10/2016I think the product will help me but I have not started using it yet!
Bill Hyres
Bill H. on 19/09/2016Looking forward to positive results from Rerum.
Kelvin S. on 23/08/2016You give 37% more product than Europe does because you sell 3.0 ML vials for the same price they sell 2.2 ml vials. Their Goleic requires refrigeration and I lost $1,000 up front because they didn't let me know that and it spoiled at room temp for two weeks when I was on vacation.
Energy tripled and pain reduced
Janie C. on 12/08/2016I have been on Rerum now for 6 months and feel fabulous . My pain has been 80% reduced and energy tripled. This has been the best treatment I have received.
Arminda G. on 10/08/2016I get excelent results against cancer

Rerum® Science

Rerum® offers Advanced Immune Support. The emulsion implements a new carrier system with the compound of Chrondroitin, Oleic Acid, Vitamin D3 and Vitamin D2 and provides the support for Macrophage Activation, that previously was assumed to GcMAF (Gc Macrophage Activating Factor). 

It is important to note that you cannot just mix all the ingredients of Rerum together to make Rerum. In Rerum®, chondroitin sulfate is non-covalently bound to Vitamin D and Oleic acid, thanks to hydrophobic/hydrophilic interactions. In effect, the secret of Rerum is in the molecular bonding.

The body's own activation of macrophages has many known effects. It contributes to our body's immune system and can help in case of a weak immune status or immune deficiencies in order to restore balance, to counteract vitality loses and to prevent susceptibility to infection. 

Download PDF on "How Does Rerum Work"

Is chondroitin sulfate responsible for the biological effects attributed to the GC protein-derived Macrophage Activating Factor (GcMAF)?
Marco Ruggiero, Heinz Reinwald, Stefania Pacini.
Medical Hypotheses 94 (2016) 126–131.

Link to Abstract   Link to Full Article

Gc Protein-Derived Macrophage Activating Factor (GcMAF) and Autism: Do Clinical Results Require a Novel Interpretation?
Marco Ruggiero.
American Journal of Immunology.

Link to Abstract   Link to Full Article

Clinical Observation of a Novel, Complementary, Immunotherapeutic Approach based on Ketogenic Diet, Rerum and Bravo.
Michael Schwalb, Margit Taubmann, Steve Hines, Heinz Reinwald, and Marco Ruggiero.
American Journal of Immunology.

Link to Abstract   Link to Full Article

Video of Molecular Biologist, Professor Marco Ruggiero, MD. PhD. discussing Rerum®

Rerum® Advantages

Rerum® offers a number of advantages compared to the previous GOleic or GcMAF:

  1. Rerum® is not derived from blood and therefore not affected by any of the problems afflicting blood-derived proteins.
  2. Rerum® is not digested by stomach acid or by stomach proteases since it is not a protein; on the contrary, its bioavailability is increased by digestion.
  3. Rerum® does not require any particular care for storage and shipping, such as special cooling or even freezing.
  4. Rerum® does not induce allergic reactions since glycosaminoglycans are notoriously non-allergenic.
  5. Rerum® is a bona fide dietary supplement since it is composed of well-known dietary supplements that have been in use for decades.
  6. Rerum® is inherently safe since it is composed of components that have been used for decades in human medicine. Chondroitin sulfate, vitamin D and oleic acid are regulated substances in the U.S. as dietary supplements, approved by the Food and Drug Administration.
  7. In Europe, chondroitin sulfate formulations are approved as drugs with evidenced efficacy and safety demonstrated by clinical trials.
  8. Rerum® is extremely bioavailable at variance with long proteins such as GcMAF.
    • This is due to the inherent flexibility of the chondroitin sulfate backbone and the presence of a fatty acid, oleic acid.
    • Thanks to this unique combination, Rerum® is rapidly absorbed via a variety of routes and is immediately bioavailable.
  9. Rerum® is nanosized.
    • This means that its contact surface is about 1,000 times wider than that of a long protein such as GcMAF.
    • Rerum® is therefore able to reach a much larger number of targets in the human body.
  10. With the invention of Rerum®, we finally have the one and only, real and safe, support for Macrophage Activation.
  11. Rerum® is manufactured in a state-of-the art GMP-certified facility in Germany.

GcMAF Immuno Therapy to strenghten the body

For many years it was erroneously believed that GcMAF (GcProtein) was a conductor in the innate immune system and an extremely powerful endogenous macrophage stimulator. 

Professor Ruggiero and a number of other research groups, however, have discovered that there are different phenotypes in humans, thus leading to different coding regions for amino acids for the human Vitamin-D binding protein (DBP). This is due to allelic differences: one group of GC polymorphism, the GC1 group, has a threonine residue whilst the GC2 group has a lysine residue. 

The possible genetic alternatives in GC1 and GC2 groups on the same genetic locus lead to completely new conclusions being drawn about GcMAF being the only protein-derived MAF (DBP) in healthy human bodies. If there are humans without a threonine coding for GcMAF, in other words subjects homozygous for GC2 and therefore with a lysine coding instead, they would not have a single molecule of GcMAF in their bodies; therefore their immune system would be weak and they would have a much higher risk of developing cancer. But this is not the case. 

On the other hand, studies around the world by many researchers have demonstrated, amongst other things, that the activation of macrophages produces pro-immunogenic, anti-inflammatory, neuro-protective and even anti-cancer/anti-angiogenetic effects. So how can we explain the efficiency of such an immune modulation via GcMAF if the entire theory surrounding GcMAG is incorrect? 

The answer seems rather simple. Professor Ruggiero believes that the answer lies in the molecular structure of GcMAF, which contains vitamin D and fatty acids, in particular oleic acid and chondroitin sulfate. The effects observed in GcMAF are solely due to its function as a carrier protein. The GcProtein itself has no effect per se; it only serves to carry the molecules endowed with all the effects erroneously attributed to GcMAF. 

And what about oleic acid and vitamin D? Could other effects previously and erroneously attributed to GcMAF be due to vitamin D and oleic acid instead? Indeed, numerous studies now show the benefits of these substances in different diseases. 

This knowledge enabled Professor Ruggiero to reconstitute all the effects and even boost the power of the aforementioned structure by designing the proper Macrophage Activating Factor: as Rerum®. This is a new generation MAF without the GcMAF protein itself. In the newly developed Rerum®, the protein backbone is replaced by chondroitin sulfate. 

While GcMAF from human blood protein only has one chemical bond for certain moieties, chondroitin has more than 50 moieties for N-Acetylgalctosamine (GalNac). Rerum® demonstrates the effects attributed to GcMAF, and even goes so far as to also show those properties that have long been linked to chondroitin sulfate.